Search results for "single-use" in Articles / App Notes
Article
Biopharma Advances Demand Specialized Expertise
Single-use disposable bioreactors and similar single-use bioprocess equipment minimize plant downtime, which is traditionally required for line clearance and product changeover. The complexity of prod…
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SEC in the Modern Downstream Purification Process
A recent trend in biopharmaceutical manufacturing is disposable or single-use technologies. If vaccine manufacturing becomes decentralized to locations throughout the world, as current trends imply, d…
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2014 Manufacturing Trends and Outlook
Hybrid equipment dominates
Hybrid manufacturing systems, which feature traditional stainless steel and disposable, single-use equipment, were used by almost three-quarters (74.4%) of the respond…
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Flexibility in Biopharmaceutical Manufacturing
Maintaining flexibility in biopharmaceutical manufacturing can deliver positive results.
By: Simon Chalk
BioPharm International
There is a high degree of consensus in the biomanuf…
Article
Cytiva to provide Arranta Bio 'idea to injection' solutions for integrated manufacturing of mRNA products
Cytiva will provide its FlexFactory single-use manufacturing platform to Arranta Bio ("Arranta"), a leading contract development and manufacturing organization (CDMO) for use in manufacturing mRNAv…
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Maximum Output Starts with Optimized Upstream Processing
She points to the mAb sector where stainless-steel bioreactors with tens of thousands of liters of capacity were commonly used for cell culture, but today have been replaced with single-use (SU) biore…
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Scaling Up an E. coli Upstream Process for Plasmid DNA Production — from 2.5 to 160 L scale Fermenters
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This article summarizes the results of Escherichia coli growth performance for plasmid production in a 5 L glass fermentor, which was scaled up to 80 and 160 L scale in Xcellerex™ X…
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Cytiva Acquires Vanrx, Innovator in Aseptic Filling
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Cytiva acquires Vanrx to extend its single-use manufacturing platform with aseptic-filling solutions.
Article
Updating Viral Clearance for New Biologic Modalities
As an example, he points to recent studies conducted on MilliporeSigma’s single-use chromatography membrane, Natrix Q. Results showed that this chromatography membrane can work across a broad range of…
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Process Development: 2020 Reflections and 2021 Possibilities
This results in higher throughput in research and process development, allowing for new opportunities for cost efficient, single-use chromatography in large-scale commercial manufacturing.
Another…