Search results for " vaccine" in Articles / App Notes
Article
Enhancing Resins Addresses Purification Concerns
Resins have been seen as one tool that can address the purification needs of new COVID-19 vaccines as well as the existing challenges in the downstream processing of increasingly complex biologic moda…
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Microbiological Testing: Time is of the Essence
Alternative strategies for in-process release of vaccine batches were needed to accelerate production of flu vaccines, with the 14-day sterility test seen as a prime target for decreasing the turnarou…
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Unifying Continuous Biomanufacturing Operations
However, using perfusion to obtain high cell densities and increase output per bioreactor volume for the production of vaccines is of interest to researchers, too (7).
No need to scale: Eliminat…
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Ensuring the Biological Integrity of Raw Materials
Contamination of biologic drugs and vaccines by adventitious agents is extremely rare. However, when contamination incidents do occur, they can be costly in terms of time and resources.
In 2010, E…
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Pandemic Alters Policies and Practices for Drug Development and Regulation
The desperate need for new vaccines and therapies to tame the deadly COVID-19 virus required new policies and procedures for how biopharma companies select, test, and manufacture medical products—and …
Article
Top Process Development Trends for 2021 and a Look into 2022
…rus (AAV) production, process workflows and considerations for messenger RNA (mRNA) therapeutics and vaccines, and efficiencies in processes development.
As we move into 2022, let’s take a look …
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High-Throughput Process Development in an Historical Environment
As an example of their utilization, Chris Daniels from Merck presented work with design and commissioning of a BSL-2 HTS platform for process development of viral vaccine production, where all liquid …
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Single-Use Technologies Prove Effective for Viral Vector Process Development
“The simple reality is that the COVID-19 pandemic has shown the benefits of single-use systems in that it would not have been possible to deploy the viral vaccines in the time and the scale that has b…
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Single-use Bioreactors Have Reached the Big Time
“Examples include traditional vaccines and blockbuster [monoclonal antibody] (mAb) biologics (>2 metric tons of mAb per year); in these cases, single-use bioreactors might not be the most efficient pr…
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Modular Manufacturing Platforms for Biologics
Therapeutic treatments produced via a modular vaccine suite—a pandemic-ready modular facility—could be a good option in the future when dealing with the proliferation of tropical diseases and regional…