Search results for " costs" in Articles / App Notes
Article
Outsourcing Trends in Biopharmaceutical Manufacturing
Trend six: Outsourcing’s growing role in cost-containment
Outsourcing is no longer a top priority when facilities are looking to reduce costs. This may largely be due to saturation and limited ret…
Article
Bioprocessing Advances in Vaccine Manufacture
SUS allow flexible manufacture when, and at the scale needed, with substantial reductions in costs and time, including presterilized equipment. In contrast, stainless-steel bioreactor-anchored facilit…
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Single-Use Technologies Prove Effective for Viral Vector Process Development
…nation rates as well as enhance the efficiency of a production facility while reducing manufacturing costs (both operational and maintenance).
While there may be some drawbacks to single-use sy…
Article
Commercial Production of Gene Therapies Using Suspension or Adherent Cell Lines
Subsequent work lasting decades improved cell line robustness and increased product titres 100-fold (4), which drove the production costs down. Cells used for gene therapy have not gone through this l…
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Genetic Vaccine Platforms Demonstrate Their Potential
She highlights a need for the reduction of costs for raw materials and manufacturing processes and improvements in stability to reduce the need for storage at low or extremely low temperatures, which …
Article
Improving mAb Manufacturing Productivity by Optimizing Buffer and Media Prep Process Flow
Raw material quality control (QC) testing can also be reduced or eliminated by implementing single-use technologies, saving time from reduced process steps as well as labor costs.
The increa…
Article
Automating the Biomanufacturing Process
Currently, this is done manually, Lebl says, and this has a direct impact on biopharmaceutical labor costs, which account for 40–50% of production costs, compared with 10–15% in other industries. “A l…
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Automation Trend in Fill/Finish Reduces Contamination Risk
“In simplest form, the larger batch sizes available within the same processing duration provide costs of goods savings,” says MacGilp.
He notes that aseptic fill/finish facilities have high overhea…
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CDMOs Driving Emerging Bio/Pharma Success
The ability of CROs to reduce clinical research costs by absorbing large numbers of clinical staff from company payrolls and implementing advanced information technology made them valuable partners fo…
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Industry Adoption of Single-Use Systems Remains Low
… is estimated that single-use manufacturing technologies can help reduce capex [capital expenditure] costs by up to 50% (2) and water and energy use by up to 80% (3) compared to a traditional facilit…