Search results for " recombinant" in Articles / App Notes
Article
Virus-like Particles as Therapeutic Moieties of the Future
These biophysical, biochemical, and immunochemical methods ensure process reproducibility and product consistency in recombinant VLPs during the manufacturing process. These characterization methods a…
Article
Technology Innovations Improve Process Chromatography Performance
“New choices for Protein A, such as, for example, a new recombinant Protein A resin developed by Avantor, [can]addresses challenges of limited supply,” Deorkar continues. “The new resin is built on a …
Article
Eliminating Residual Impurities Starts with a Strategic Plan
EDQM, EurPh, Products of Recombinant DNA Technology (0784) (Strasborg, France).
4. USP, USP General Chapter , “Residual Host Cell Protein Measurement in Biopharmaceuticals,” USP 39-NF 34 (Rockvil…
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Biomanufacturing: Demand for Continuous Bioprocessing Increasing
Some commercial biopharmaceutical products that essentially require perfusion’s generally milder/less intense processing conditions, including Factor VIII (the largest recombinant molecule biopharmace…
Article
Mapping a Route for Cell and Gene Therapy Process Development
On a big-picture level, the increased demand for viral-vector manufacturing services to support clinical trials for recombinant adeno-associated virus (rAAV)-based gene therapies has led to a shortage…
Article
Why, Why, Why…ELISA? A Look at the Benchmark HCP Assay
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Biologics developers and manufacturers demand an accurate and reliable assay for host cell protein (HCP) quantitation. Let’s take a close look at why analytica…
Article
News: Cytiva Adds ELISA Kit to End-to-End HCP Monitoring Capabilities
Cytiva is pleased to announce the new Amersham HCPQuant CHO kit, a generic for detecting host cell protein impurities in drug samples produced in CHO cell lines.
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Advances in Engineering of Protein-Based APIs
Advances in Engineering of Protein-Based APIs
New platform technologies, advanced modeling tools, and addressing patient needs are important developments.
By Cynthia A. Challener
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Article
A Look at the Affinity Chromatography Landscape
“Engineered recombinant Protein A resins with smaller bead sizes are often suitable for bispecific antibodies with Fc regions, while for bispecific molecules without Fc regions, other affinity resins …
Article
Achieving Process Balance with Perfusion Bioreactors
Advances in single-use technologies, sensors, and cell retention systems facilitate processes designed for the long run.
By Cynthia A. Challener
MG/Stock.Adobe.com
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