Search results for " specification" in Articles / App Notes

Article Optimizing Resin Performance with Disposable Chromatography Solutions
Although the initial uptake of single-use chromatography solutions has been relatively slow, an increased need for higher-capacity resins and the demand for smaller batches has made disposable chrom…

Article New Era for Generic Drugs
Manufacturers face regulatory overhaul, while brand-generic debates escalate over biosimilars and labeling changes. Nov 1, 2014 By: Jill Wechsler BioPharm International Volume 11, Issue …

Article Viral Clearance Challenges in Bioprocessing
Challenges remain for virus removal and validation. Nov 1, 2014 By: Cynthia Challener, PhD BioPharm International Volume 11, Issue 27, pp. 42-44 Removal and inactivation of adventitio…

Article Novel Vaccine Technologies Meet the Need for Pandemic and Therapeutic Solutions
New approaches to vaccine production are targeting rapid supply for pandemic situations and broadly effective therapeutic treatments. Following the 2009 outbreak of the H1N1 pandem…

Article Manufacturers Struggle with Breakthrough Drug Development
The regulator understands that evaluations based on limited stability data and provisional specifications could mask safety issues and that permitting manufacturers to shift more CMC analysis and fina…

Article Predicting Progress in Protein Aggregation
Techniques to enable the design and formulation of stable, protein-based therapeutics. In silico analysis and the evaluation of formulability, aided by new analytical tools such as hydrogen deut…

Article Best Practices in Adopting Single-Use Systems
Key considerations for implementing single-use components or platforms when moving from research to process development. The adoption of single-use systems in biopharmaceutical production or…

Article Operational Excellence: More Than Just Process Improvement
By embracing efficiency and quality, biopharmaceutical organizations can work better and achieve better work. Life-sciences companies face more pressure than ever to reduce costs and increase eff…

Article Elucidating Biosimilars Characterization
The global market for biosimilar drugs has been forecasted to be $2.445 billion in 2013 according to a report by the British market-research firm, Visiongain (1). The growth corresponds to a …

Article HT Multi-Product Liquid Chromatography for Characterization of Monoclonal Antibodies
Q6B, Specifications: test procedures and acceptance criteria for biotechnological/biological products. Geneva, Switzerland; 1999. 4. US Food and Drug Administration. Guidance for industry. Points …

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