Search results for " monoclonal"
Article
Top Tips for Successful Development of Antibody Chromatography Processes
I'm joined today by Jakob Liderfelt, a Global Product Manager for monoclonal antibody polishing with Cytiva. Jakob, thank you so much for your time today.
Jakob Liderfelt: It's very nice …
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Selecting Chromatography Resins for Bispecific Antibody Purification
Their purification can be more challenging than traditional monoclonal antibodies (mAbs), however, due to the increased level of product-related impurities with high similarity to the desired bsAbs. A…
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Top challenges in recombinant protein purification process development
First of all, why can process development be much more complex for recombinant proteins compared to traditional monoclonal antibodies?
Emma Lind: Yes. Well, for recombinant proteins, you often don…
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Pulling Out All the Stops in mAb Manufacturing
While the biopharma industry is pushing the barriers with antibody development, it must also contend with contemporary challenges in bulk monoclonal antibody (mAb) manufacturing. The need for…
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Pushing the Barriers in Next-Gen Antibody Development
Continued development of new and next-generation antibodies is spurred by the increasing demand for more effective and custom-tailored biologic therapies. In particular, bispecific antibodi…
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eBook: Purification of Antibody Therapeutics - Approach for Diversified Pipeline
Over the years, development beyond traditional monoclonal antibodies (mAbs) has increased. Today, we see multispecific and bispecific antibodies, antibody fragments, and antibody drug conjugates in th…
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Optimizing your Cell Culture Process to Improve Productivity
It could also be used to analyze monoclonal antibody protein quality by examining the parameters, supplements, and feed timings, which may help increase the quality of the protein being produced in cu…
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What’s in your media? How costly is variability of cell culture media to your manufacturing process?
There have been numerous studies which have been done looking at trace metal effects on monoclonal antibodies. Some of the studies performed investigated the glycosylation patterns. For example, the s…
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Get to know: mAb variants - eLearning
Cytiva has published an interactive course that gives an overview of monoclonal antibodies (mAbs) and current variants used and developed in academia and industry.
Key learnings are:
- Structure…
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Enhancing Resins Addresses Purification Concerns
There are, however, similarities in certain classes of biologics, such as monoclonal antibodies. “Because traditional monoclonal immunoglobulin G (IgG) products share a similar structural and chemical…