Search results for "flexible"

Article Taking a “Development-by-Design” Approach to Cell Therapies
It needs to be flexible at the early stages,” Hampson says. “But, as you near Phase III, you need to lock in your process.” Table II summarizes issues and points where changes will be easier. Tabl…

Article Quality Systems Key to Lifecycle Drug Management
A more flexible change management approach has been encouraged in the European Union as part of an effort to reduce “variations” that require prior approval, pointed out Jean-Louis Robert, head of the…

Article Ensuring the Quality of Biologicals
May 02, 2015 By Stephen Wicks, PhD Pharmaceutical Technology Volume 39, Issue 5 The European Pharmacopoeia (Ph. Eur.), which celebrated its 50th anniversary in 2014, provides common …

Article Modern Manufacturing Systems Key to FDA Quality Initiative

Article Implementation of Raw Material Control Strategies in the Manufacture of Single-Use Bioprocessing Containers
The authors review efforts to limit polymer degradation without significantly impeding cell growth. Jan 01, 2015 By Sara Ullsten, Shujian Yi, Jeffrey Carter, Eva Lindskog, Pokon Ganguli, Her…

Article Technologies and Practices Must Evolve to Meet Demand
Jan 01, 2015  By Rita Peters Through Dec. 3, 2014, nearly 30% of FDA’s new drug approvals for 2014 were for biologic-based therapies, up from 7% in 2013 (1). As the percentage of large-molecule …

Article Optimizing Resin Performance with Disposable Chromatography Solutions
Although the initial uptake of single-use chromatography solutions has been relatively slow, an increased need for higher-capacity resins and the demand for smaller batches has made disposable chrom…

Article Biopharma Manufacturers Respond to Ebola Crisis
Demand for new therapies and vaccines spotlights production challenges. Oct 1, 2014 By: Jill Wechsler BioPharm International Volume 27, Issue 10, pp. 8-9 The development of new tr…

Article Pharma Investments Reflect Key Industry Trends
Shrinking facility size, growth of biologics, and emerging market demand influence pharma investments. Aug 2, 2014 By: Cynthia Challener, PhD Pharmaceutical Technology Volume 37, Iss…

Article Relationship Building at Top of Mind for Clients
Annual study shows technical expertise is not enough. Aug 1, 2014 By: Eric Langer BioPharm International Volume 27, Issue 8, pp. 12-14 Contract manufacturing organizations (CMOs) shou…

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