Search results for " purification" in Articles / App Notes
Article
Accelerating CMC - The future of process development is in silico
Presented by Per Liden, General Manager, GoSilico at Cytiva.
Simulation for in silico process development is becoming a viable option to reduce the time needed for chemicals, manufacturin…
Article
Developing a HIC polishing step for removal of mAb aggregates
This article describes the development of a flow-through (FT) polishing step using hydrophobic interaction chromatography (HIC) to remove mAb aggregates.
It includes:
- The use of HTPD plate…
Article
On-demand: ÄKTA process™ system virtual demo
Improving usability, efficiency, and reliability were our focus when we designed the new ÄKTA process™ system.
In this virtual workshop Torbjörn Blank will explain how the ÄKTA pr…
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Announcing ÄKTA ready™ extended single-use system
ÄKTA ready™ extended system is a single-use liquid chromatography system designed for process scale-up and GMP manufacturing.
The system uses disposable flow paths and prepacked …
Article
Manufacturing mRNA for research and beyond
This eBook guides you in the practical aspects of setting up an mRNA research laboratory. Get insights on methods, materials, and workflows for mRNA synthesis and scale up.
Explore the mRNA…
Article
See a chromatography modeling software in action
Mechanistic models use computer simulations to decrease the number of experiments you need during process development.
The simulations are based on known physiochemical phenomena involved in ch…
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Report from the 12th Plasma Product Biotechnology Forum
The model output was a prediction of yield and purification rate, and the input included feed flowrate, conductivity, column loading, and total protein concentration. One of the conclusions from the s…
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Create Digital Twins of your Chromatography Processes
The benefit of a mechanistic model? You can test thousands of purification options in a few hours.
GoSilico™ Chromatography Modeling Software creates digital twins of downstream processes usin…
Article
Good Modeling Practice
How to ensure accurate model calibration for your mechanistic models.
Mechanistic models have become a very promising technique to describe chromatography processes. These models …
Article
How to optimize AAV capsid separation
In this free, interactive course you’ll learn how to tackle one of the key challenges in Adeno-associated virus (AAV) manufacturing–separating full and empty capsids in the polishing step. You’ll …