Search results for " purification"
Poster
Purification of monoclonal antibodies using modern chromatography media and membranes
This white paper is a guide to the development of MAb purification platforms and provides an overview of Cytiva’s offering of process chromatography media (resins) and membranes for MAb purification…
Article
A Platform Approach for the Purification of Domain Antibodies (Dabs)
All purification steps were optimized by Design of Experiments (DoE), thereby supporting a Quality by Design (QbD) approach.
Using Capto L, Capto MMC ImpRes, and Capto adhere ImpRes media in …
Article
Purification strategies for antibody-derived entities: bispecifics and fragments
The diversity of antibody variants in today’s pipeline presents unique challenges for purification. Purification platforms used for many monoclonal antibodies (mAbs) need to be adopted for ant…
Article
A scalable single-use two-step plasmid purification process
…uirement for a reliable source of high-quality plasmid DNA (pDNA), which typically requires multiple purification steps to achieve.
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Article
Optimization of a two-step purification method for bispecific antibodies
This presentation shows the results from Cytiva collaborating with Alligator to develop an efficient downstream purification process for a cancer immunotherapy bispecific antibody (bsAb). A two-step p…
Article
mRNA: The Messenger - mRNA Product Purification
Join us for part 4 of mRNA : the messenger, where we discuss key considerations for the purification of the mRNA product, including the various methods available and how to consider scalability and su…
Article
Accelerating VLP purification process development
The development of a purification strategy is a mainly experimental approach where parameters are optimized via Design-of-Experiment (DoE) studies. Dozens of experiments are needed to screen a process…
Webcast
The GMP of AAV: Purification for Clinical Production
Last, we’ll explore what’s on the horizon for systems and other purification techniques designed for purifying AAV according to good manufacturing practices (GMP) requirements.
Article
The GMP of AAV: Purification for Clinical Production
Watch this presentation to learn about the key considerations when developing a purification process for adeno-associated viruses (AAV).
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Article
Case Study: High Throughput mAb Purification Using Fibro
In this case study, a drug discovery lab at AstraZeneca finds that purifying antibodies with Fibro PrismA means they can screen more candidates per week with a simpler equipment setup.
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